Choosing Your Technologies When You Start
The most important initial consideration is the nature of innovation for your particular startup. Is your innovation primarily a social/behavioral/market structure one (think Instagram, Tumblr, Etsy) or a technical one (think v1 of Google, Twilio)? If it is the former you should tend to go conservative in your technology choices whereas in the latter you must pick something risky.
Choosing Your Technologies When You Start